Song-I Han

Research Overview

The Han Lab pushes the frontiers of magnetic resonance spectroscopy and relaxometry for the study of biomolecular interactions, biomolecular and materials surfaces, and the property of their hydration layers. The particular emphasis is on the interrogation of interfaces and local structures through locally amplified NMR spectroscopy of materials and biological systems around electron spin “sensors” and "antennas". The study of local features at the nanometer and sub-nanometer scale is achieved through the use of strategically placed or intrinsically located electron spin probes and sites, and orders of magnitudes in NMR signal enhancements, achieved through the polarization transfer from the electron spin probes to the surrounding nuclear spins, relying on processed broadly termed dynamic nuclear polarization (DNP).