Image placeholder

A major goal of CALS-affiliated researchers is to reveal the fundamental biological basis of aging by understanding the molecules that regulate age progression and how aging mechanisms operate in cells. Our investigators perform studies on readily cultivated model animals and cells grown in the laboratory to illuminate the changes that occur as aging proceeds, how lifespan and aging programs can be experimentally modified, and how resilience against age-promoted degeneration can be promoted. Researchers are also investigating approaches to creating tissues and organs that can be used in regenerative medicine. Discoveries from this research can lead to improved methods for slowing, and even reversing, the aging process in humans.

 

Affiliated Researchers

Associate Professor, Anthropology
Comparative biology of cancer, human cancer in evolutionary perspective
Distinguished Professor, Chemistry & Biochemistry
Amyloid assembly in age-related neurodegenerative disease
Adjunct Professor UCSB
Associate Professor
Geroscience Center for Brain Health and Metabolism
University of Chile
Role of mitochondria in cellular senescence, development of drugs that extend healthspan, identification of senescence biomarkers
Professor, Molecular, Cellular, and Developmental Biology
Aging and regeneration in basal chordates
Assistant Professor
Chemical Engineering
Biological Engineering
Epigenetic mechanisms of aging
Professor, Molecular, Cellular, and Development Biology
Alzheimer's and age-related neurodegenerative disease
Assistant Professor, Molecular, Cellular, & Developmental Biology
The role of peroxisome dysfunction in aging-related diseases
Professor
Chemistry and Biochemistry
Chemical Engineering
Age-related tau aggregation in age-related neurodegenerative disease
Senior Scientist and Director of Scientific Communication, CALS
Aging and longevity research; analysis and communication of rigorous evidence-based intervention in aging and lifespan extension.
Distinguished Professor
Harriman Professor of Neuroscience
Molecular, Cellular, and Developmental Biology
Alzheimer's and age-related neurodegenerative disease
Duggan Professor and Distinguished Professor
Molecular, Cellular, and Developmental Biology
Impact of aging on the senses and animal behavior
Duggan Professor and Distinguished Professor
Molecular, Cellular, & Developmental Biology
Revitalizing dying cells
Assistant Professor, Molecular, Cellular, & Developmental Biology
DNA repair in aging
Director and Founder, CALS
Distinguished Professor
Wilcox Family Chair in Biotechnology
Director, Biomolecular Science and Engineering
Mechanisms of aging, longevity, and resilience
Professor, Molecular, Cellular, and Developmental Biology
Metabolic therapies in extension of healthspan and lifespan
Assistant Professor, Molecular, Cellular, & Developmental Biology
Systems level mechanisms of cellular dysfunction caused by age-related decline and mechanisms for reversal
Professor, Ecology, Evolution and Marine Biology
Cellular and epigenetic mechanisms of aging, evolution and age-related diseases